Intensified Mycophenolate Mofetil Dosing and Higher Mycophenolic Acid Trough Levels Reduce Severe Acute Graft-versus-Host Disease After Double-Unit Cord Blood Transplantation

While mycophenolate mofetil (MMF) has replaced corticosteroids as immunosuppression in cord blood transplantation (CBT), optimal MMF dosing has yet to be established. We intensified MMF dosing from every 12 to 8 hours to augment graft-versus-host disease (GVHD) prophylaxis in double-unit CBT (dCBT)...

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Publicado en:Biol Blood Marrow Transplant
Autores principales: Harnicar, S., Ponce, D.M., Hilden, P., Zheng, J., Devlin, S.M., Lubin, M., Pozotrigo, M., Mathew, S., Adel, N., Kernan, N.A., O'Reilly, R., Prockop, S., Scaradavou, A., Hanash, A., Jenq, R., van den Brink, M., Giralt, S., Perales, M.A., Young, J.W., Barker, J.N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408232/
https://ncbi.nlm.nih.gov/pubmed/25687796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.01.024
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