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Hyperplastic Growth of Pulmonary Artery Smooth Muscle Cells from Subjects with Pulmonary Arterial Hypertension Is Activated through JNK and p38 MAPK

Smooth muscle in the pulmonary artery of PAH subjects, both idiopathic and hereditary, is characterized by hyperplasia. Smooth muscle cells (HPASMC) isolated from subjects with or without PAH retain their in vivo phenotype as illustrated by their expression of alpha-smooth muscle actin and expressio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wilson, Jamie L., Yu, Jun, Taylor, Linda, Polgar, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408087/
https://ncbi.nlm.nih.gov/pubmed/25905460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123662
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