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Substrate Tunnels in Enzymes: Structure-Function Relationships and Computational Methodology

In enzymes, the active site is the location where incoming substrates are chemically converted to products. In some enzymes, this site is deeply buried within the core of the protein and in order to access the active site, substrates must pass through the body of the protein via a tunnel. In many sy...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Kingsley, Laura J., Lill, Markus A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404149/
https://ncbi.nlm.nih.gov/pubmed/25663659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24772
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