Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16

BACKGROUND: Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a pivotal role in cancer biology. However, the overall biological role and clinical significance of PVT1 in gastric carcinogenesis remains largely unknown. METHODS: Expression of PVT1 was analyzed in 80 GC tissues...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cancer
Main Authors: Kong, Rong, Zhang, Er-bao, Yin, Dan-dan, You, Liang-hui, Xu, Tong-peng, Chen, Wen-ming, Xia, Rui, Wan, Li, Sun, Ming, Wang, Zhao-xia, De, Wei, Zhang, Zhi-hong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399399/
https://ncbi.nlm.nih.gov/pubmed/25890171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0355-8
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