Setd1a regulates progenitor B-cell-to-precursor B-cell development through histone H3 lysine 4 trimethylation and Ig heavy-chain rearrangement

SETD1A is a member of trithorax-related histone methyltransferases that methylate lysine 4 at histone H3 (H3K4). We showed previously that Setd1a is required for mesoderm specification and hematopoietic lineage differentiation in vitro. However, it remains unknown whether or not Setd1a controls spec...

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Bibliographic Details
Published in:FASEB J
Main Authors: Tusi, Betsabeh Khoramian, Deng, Changwang, Salz, Tal, Zeumer, Leilani, Li, Yangqiu, So, Chi Wai Eric, Morel, Laurence M., Qiu, Yi, Huang, Suming
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2015
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396605/
https://ncbi.nlm.nih.gov/pubmed/25550471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-263061
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