Renal Tubule Angiotensin II Type 1 Receptor–Associated Protein Promotes Natriuresis and Inhibits Salt‐Sensitive Blood Pressure Elevation

BACKGROUND: Angiotensin II type 1 receptor (AT1R)–associated protein (ATRAP; Agtrap gene) promotes AT1R internalization along with suppression of pathological AT1R activation. In this study, we examined whether enhancement of ATRAP in the renal distal tubules affects sodium handling and blood pressu...

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Detaylı Bibliyografya
Yayımlandı:J Am Heart Assoc
Asıl Yazarlar: Wakui, Hiromichi, Uneda, Kazushi, Tamura, Kouichi, Ohsawa, Masato, Azushima, Kengo, Kobayashi, Ryu, Ohki, Kohji, Dejima, Toru, Kanaoka, Tomohiko, Tsurumi‐Ikeya, Yuko, Matsuda, Miyuki, Haruhara, Kotaro, Nishiyama, Akira, Yabana, Machiko, Fujikawa, Tetsuya, Yamashita, Akio, Umemura, Satoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392439/
https://ncbi.nlm.nih.gov/pubmed/25792129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001594
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