Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease

BACKGROUND: Chronic liver injury can lead to the development of liver fibrosis and cirrhosis but only in a minority of patients. Currently, it is not clear which factors determine progression to fibrosis. We investigated whether DNA\methylation profile as determined by pyrosequencing can distinguish...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Zeybel, Müjdat, Hardy, Timothy, Robinson, Stuart M, Fox, Christopher, Anstee, Quentin M, Ness, Thomas, Masson, Steven, Mathers, John C, French, Jeremy, White, Steve, Mann, Jelena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391139/
https://ncbi.nlm.nih.gov/pubmed/25859289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0056-6
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