Potassium Channel Activator Attenuates Salicylate-Induced Cochlear Hearing Loss Potentially Ameliorating Tinnitus

High dose sodium salicylate causes moderate, reversible hearing loss and tinnitus. Salicylate-induced hearing loss is believed to arise from a reduction in the electromotile response of outer hair cells (OHCs) and/or reduction of KCNQ4 potassium currents in OHCs, which decreases the driving force fo...

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Vydáno v:Front Neurol
Hlavní autoři: Sun, Wei, Liu, Jun, Zhang, Chao, Zhou, Na, Manohar, Senthilvelan, Winchester, Wendy, Miranda, Jason A., Salvi, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387930/
https://ncbi.nlm.nih.gov/pubmed/25904892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2015.00077
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