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Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring

Artemisinin-based drugs are the front-line weapon in the treatment of human malaria cases, but there is concern that recent reports of slow clearing infections may signal developing resistance to treatment. In the absence of molecular markers for resistance, current efforts to monitor drug efficacy...

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Detalhes bibliográficos
Publicado no:Evol Appl
Main Authors: Pollitt, Laura C, Sim, Derek, Salathé, Rahel, Read, Andrew F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380923/
https://ncbi.nlm.nih.gov/pubmed/25861387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.12194
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