Screening of Drugs to Treat 8p11 Myeloproliferative Syndrome Using Patient-Derived Induced Pluripotent Stem Cells with Fusion Gene CEP110-FGFR1

Induced pluripotent stem (iPS) cells provide powerful tools for studying disease mechanisms and developing therapies for diseases. The 8p11 myeloproliferative syndrome (EMS) is an aggressive chronic myeloproliferative disorder (MPD) that is caused by constitutive activation of fibroblast growth fact...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Yamamoto, Shohei, Otsu, Makoto, Matsuzaka, Emiko, Konishi, Chieko, Takagi, Haruna, Hanada, Sachiyo, Mochizuki, Shinji, Nakauchi, Hiromitsu, Imai, Kohzoh, Tsuji, Kohichiro, Ebihara, Yasuhiro
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372437/
https://ncbi.nlm.nih.gov/pubmed/25803811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120841
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