Screening of Drugs to Treat 8p11 Myeloproliferative Syndrome Using Patient-Derived Induced Pluripotent Stem Cells with Fusion Gene CEP110-FGFR1

Induced pluripotent stem (iPS) cells provide powerful tools for studying disease mechanisms and developing therapies for diseases. The 8p11 myeloproliferative syndrome (EMS) is an aggressive chronic myeloproliferative disorder (MPD) that is caused by constitutive activation of fibroblast growth fact...

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Veröffentlicht in:PLoS One
Hauptverfasser: Yamamoto, Shohei, Otsu, Makoto, Matsuzaka, Emiko, Konishi, Chieko, Takagi, Haruna, Hanada, Sachiyo, Mochizuki, Shinji, Nakauchi, Hiromitsu, Imai, Kohzoh, Tsuji, Kohichiro, Ebihara, Yasuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372437/
https://ncbi.nlm.nih.gov/pubmed/25803811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120841
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