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Natural Selection in a Bangladeshi Population from the Cholera-Endemic Ganges River Delta

As an ancient disease with high fatality, cholera has likely exerted strong selective pressure on affected human populations. We performed a genome-wide study of natural selection in a population from the Ganges River Delta, the historic geographic epicenter of cholera. We identified 305 candidate s...

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Publicat a:Sci Transl Med
Autors principals: Karlsson, Elinor K., Harris, Jason B., Tabrizi, Shervin, Rahman, Atiqur, Shlyakhter, Ilya, Patterson, Nick, O'Dushlaine, Colm, Schaffner, Stephen F., Gupta, Sameer, Chowdhury, Fahima, Sheikh, Alaullah, Shin, Ok Sarah, Ellis, Crystal, Becker, Christine E., Stuart, Lynda M., Calderwood, Stephen B., Ryan, Edward T., Qadri, Firdausi, Sabeti, Pardis C., LaRocque, Regina C.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367964/
https://ncbi.nlm.nih.gov/pubmed/23825302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006338
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