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Inhibition of NF-kappa B signaling restores responsiveness of castrate resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor variants expression
Androgen receptor splicing variants (ARVs) which lack the ligand-binding domain (LBD) are associated with the development of castration-resistant prostate cancer (CRPC), including resistance to the new generation of high affinity anti-androgens. However, the mechanism by which ARVs expression is reg...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Oncogene |
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Prif Awduron: | , , , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
2014
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362792/ https://ncbi.nlm.nih.gov/pubmed/25220414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.302 |
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