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Rational stabilization of complex proteins: a divide and combine approach

Increasing the thermostability of proteins is often crucial for their successful use as analytic, synthetic or therapeutic tools. Most rational thermostabilization strategies were developed on small two-state proteins and, unsurprisingly, they tend to fail when applied to the much more abundant, lar...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Lamazares, Emilio, Clemente, Isabel, Bueno, Marta, Velázquez-Campoy, Adrián, Sancho, Javier
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360737/
https://ncbi.nlm.nih.gov/pubmed/25774740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09129
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