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Rational stabilization of complex proteins: a divide and combine approach

Increasing the thermostability of proteins is often crucial for their successful use as analytic, synthetic or therapeutic tools. Most rational thermostabilization strategies were developed on small two-state proteins and, unsurprisingly, they tend to fail when applied to the much more abundant, lar...

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מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Lamazares, Emilio, Clemente, Isabel, Bueno, Marta, Velázquez-Campoy, Adrián, Sancho, Javier
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360737/
https://ncbi.nlm.nih.gov/pubmed/25774740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09129
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