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Rational stabilization of complex proteins: a divide and combine approach
Increasing the thermostability of proteins is often crucial for their successful use as analytic, synthetic or therapeutic tools. Most rational thermostabilization strategies were developed on small two-state proteins and, unsurprisingly, they tend to fail when applied to the much more abundant, lar...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360737/ https://ncbi.nlm.nih.gov/pubmed/25774740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09129 |
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