Dexamethasone in osteogenic medium strongly induces adipocyte differentiation of mouse bone marrow stromal cells and increases osteoblast differentiation

BACKGROUND: Osteoblasts and adipocytes share a common mesenchymal stem cell origin. Therefore, it has been suggested that the accumulation of marrow adipocytes observed in bone loss is caused by a shift in the commitment of mesenchymal stem cells from the osteogenic pathway to the adipogenic pathway...

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Udgivet i:BMC Cell Biol
Main Authors: Ghali, Olfa, Broux, Odile, Falgayrac, Guillaume, Haren, Nathalie, van Leeuwen, Johannes PTM, Penel, Guillaume, Hardouin, Pierre, Chauveau, Christophe
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359404/
https://ncbi.nlm.nih.gov/pubmed/25887471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0056-6
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