Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade extracellular matrix (ECM), thus assisting invasion. Upregulation of MMPs, frequently reported in gliomas, is associated with aggressive behavior. WNK2 is a tumor suppressor gene expressed in normal brain, and silenced by promoter...

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Vydáno v:Oncotarget
Hlavní autoři: Costa, Angela Margarida, Pinto, Filipe, Martinho, Olga, Oliveira, Maria José, Jordan, Peter, Reis, Rui Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359304/
https://ncbi.nlm.nih.gov/pubmed/25596741
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