Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade extracellular matrix (ECM), thus assisting invasion. Upregulation of MMPs, frequently reported in gliomas, is associated with aggressive behavior. WNK2 is a tumor suppressor gene expressed in normal brain, and silenced by promoter...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Costa, Angela Margarida, Pinto, Filipe, Martinho, Olga, Oliveira, Maria José, Jordan, Peter, Reis, Rui Manuel
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359304/
https://ncbi.nlm.nih.gov/pubmed/25596741
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