Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment

Reprogramming of metabolism is a well-established property of cancer cells that is receiving growing attention as potential therapeutic target. Oral squamous cell carcinomas (OSCC) are aggressive and drugs-resistant human tumours displaying wide metabolic heterogeneity depending on their malignant g...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ruggieri, Vitalba, Agriesti, Francesca, Scrima, Rosella, Laurenzana, Ilaria, Perrone, Donatella, Tataranni, Tiziana, Mazzoccoli, Carmela, Lo Muzio, Lorenzo, Capitanio, Nazzareno, Piccoli, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359228/
https://ncbi.nlm.nih.gov/pubmed/25544754
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