Involvement of the Cdc42 Pathway in CFTR Post-Translational Turnover and in Its Plasma Membrane Stability in Airway Epithelial Cells

Cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel that is expressed on the apical plasma membrane (PM) of epithelial cells. The most common deleterious allele encodes a trafficking-defective mutant protein undergoing endoplasmic reticulum-associated degradation (ERAD)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ferru-Clément, Romain, Fresquet, Fleur, Norez, Caroline, Métayé, Thierry, Becq, Frédéric, Kitzis, Alain, Thoreau, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359135/
https://ncbi.nlm.nih.gov/pubmed/25768293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118943
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