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The Yin and Yang aspects of IL-27 in induction of cancer-specific T-cell responses and immunotherapy
Accumulating evidences from animal studies have indicated that both endogenous and exogenous IL-27, an IL-12 family of cytokine, can increase antitumor T-cell activities and inhibit tumor growth. IL-27 can modulate Treg responses, and program effector T cells into a unique T-effector stem cell (T(SE...
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| 發表在: | Immunotherapy |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4356131/ https://ncbi.nlm.nih.gov/pubmed/25713993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.14.95 |
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