The Yin and Yang aspects of IL-27 in induction of cancer-specific T-cell responses and immunotherapy

Accumulating evidences from animal studies have indicated that both endogenous and exogenous IL-27, an IL-12 family of cytokine, can increase antitumor T-cell activities and inhibit tumor growth. IL-27 can modulate Treg responses, and program effector T cells into a unique T-effector stem cell (T(SE...

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Bibliographic Details
Published in:Immunotherapy
Main Authors: Li, Ming-Song, Liu, Zhenzhen, Liu, Jin-Qing, Zhu, Xiaotong, Liu, Zhihao, Bai, Xue-Feng
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356131/
https://ncbi.nlm.nih.gov/pubmed/25713993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.14.95
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