Suppression of Laser-Induced Choroidal Neovascularization by the Oral Medicine Targeting Histamine Receptor H4 in Mice

PURPOSE: This study aimed to examine relationship of histamine receptor H4 (HRH4) and the pathogenesis of laser-induced choroidal neovascularization (laser-CNV) and to determine whether oral administration of HRH4 antagonists suppressed laser-CNV in mice. METHODS: Laser photocoagulation was performe...

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Veröffentlicht in:Transl Vis Sci Technol
Hauptverfasser: Ijima, Ryo, Kaneko, Hiroki, Ye, Fuxiang, Takayama, Kei, Nagasaka, Yosuke, Kataoka, Keiko, Funahashi, Yasuhito, Iwase, Takeshi, Kachi, Shu, Kato, Seiichi, Terasaki, Hiroko
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356033/
https://ncbi.nlm.nih.gov/pubmed/25774332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.4.2.6
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