Spatial Positioning of All 24 Chromosomes in the Lymphocytes of Six Subjects: Evidence of Reproducible Positioning and Spatial Repositioning following DNA Damage with Hydrogen Peroxide and Ultraviolet B

The higher-order organization of chromatin is well-established, with chromosomes occupying distinct positions within the interphase nucleus. Chromatin is susceptible to, and constantly assaulted by both endogenous and exogenous threats. However, the effects of DNA damage on the spatial topology of c...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Ioannou, Dimitrios, Kandukuri, Lakshmi, Quadri, Ameer, Becerra, Victor, Simpson, Joe Leigh, Tempest, Helen G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355486/
https://ncbi.nlm.nih.gov/pubmed/25756782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118886
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