Metalloprotease NleC Suppresses Host NF-κB/Inflammatory Responses by Cleaving p65 and Interfering with the p65/RPS3 Interaction

Attaching/Effacing (A/E) pathogens including enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC) and the rodent equivalent Citrobacter rodentium are important causative agents of foodborne diseases. Upon infection, a myriad of virulence proteins (effectors) encoded by A/E path...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Hodgson, Andrea, Wier, Eric M., Fu, Kai, Sun, Xin, Yu, Hongbing, Zheng, Wenxin, Sham, Ho Pan, Johnson, Kaitlin, Bailey, Scott, Vallance, Bruce A., Wan, Fengyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355070/
https://ncbi.nlm.nih.gov/pubmed/25756944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004705
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