Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease

Glutamatergic systems play a critical role in cognitive functions and are known to be defective in Alzheimer’s disease (AD) patients. Previous literature has indicated that glial glutamate transporter EAAT2 plays an essential role in cognitive functions and that loss of EAAT2 protein is a common phe...

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Gepubliceerd in:J Exp Med
Hoofdauteurs: Takahashi, Kou, Kong, Qiongman, Lin, Yuchen, Stouffer, Nathan, Schulte, Delanie A., Lai, Liching, Liu, Qibing, Chang, Ling-Chu, Dominguez, Sky, Xing, Xuechao, Cuny, Gregory D., Hodgetts, Kevin J., Glicksman, Marcie A., Lin, Chien-Liang Glenn
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354363/
https://ncbi.nlm.nih.gov/pubmed/25711212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140413
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