Dosage and Temporal Thresholds in microRNA Proteomics

MicroRNAs (miRNAs) modulate protein and mRNA expression through translational repression and/or mRNA decay. In this study, we combined SILAC-based proteomics and RNAseq to identify primary targets based on measurements of protein and mRNA repression and analysis of transcript 3′UTR sequences. The pr...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Lee, Thomas, Wang, Nan, Houel, Stephane, Couts, Kasey, Old, William, Ahn, Natalie
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350026/
https://ncbi.nlm.nih.gov/pubmed/25467838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.043851
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