Next-Generation Sequencing Reveals a Controlled Immune Response to Zaire Ebola Virus Challenge in Cynomolgus Macaques Immunized with Vesicular Stomatitis Virus Expressing Zaire Ebola Virus Glycoprotein (VSVΔG/EBOVgp)

Vesicular stomatitis virus expressing Zaire Ebola virus (EBOV) glycoprotein (VSVΔG/EBOVgp) could be used as a vaccine to meet the 2014 Ebola virus outbreak. To characterize the host response to this vaccine, we used mRNA sequencing to analyze peripheral blood mononuclear cells (PBMCs) from cynomolgu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Vaccine Immunol
Prif Awduron: Barrenas, Fredrik, Green, Richard R., Thomas, Matthew J., Law, G. Lynn, Proll, Sean C., Engelmann, Flora, Messaoudi, Ilhem, Marzi, Andrea, Feldmann, Heinz, Katze, Michael G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Vaccines
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340895/
https://ncbi.nlm.nih.gov/pubmed/25589554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00733-14
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