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Discoidin domain receptor 2 signaling networks and therapy in lung cancer
Discoidin domain receptor 2 (DDR2) is an atypical receptor tyrosine kinase that binds to and is activated by collagen in the extracellular matrix. Recent exon sequencing studies have identified DDR2 to be mutated with a 3-4% incidence in squamous cell cancers (SCCs) of the lung. This article summari...
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| Pubblicato in: | J Thorac Oncol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340565/ https://ncbi.nlm.nih.gov/pubmed/24828669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000164 |
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