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Discoidin domain receptor 2 signaling networks and therapy in lung cancer

Discoidin domain receptor 2 (DDR2) is an atypical receptor tyrosine kinase that binds to and is activated by collagen in the extracellular matrix. Recent exon sequencing studies have identified DDR2 to be mutated with a 3-4% incidence in squamous cell cancers (SCCs) of the lung. This article summari...

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Foilsithe in:J Thorac Oncol
Main Authors: Payne, Leo S., Huang, Paul H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340565/
https://ncbi.nlm.nih.gov/pubmed/24828669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000164
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