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De novo asymmetric synthesis of the mezzettiaside family of natural products via the iterative use of a dual B-/Pd-catalyzed glycosylation

The first synthesis of any and all members of the mezzettiaside family of natural products has been achieved. The reported synthesis features the iterative use of the Taylor catalyst in a dual nucleophilic boron/electrophilic palladium catalyzed regioselective glycosylation. In addition, the de novo...

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Pubblicato in:Chem Sci
Autori principali: Bajaj, Sumit O., Sharif, Ehesan U., Akhmedov, Novruz G., O'Doherty, George A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339001/
https://ncbi.nlm.nih.gov/pubmed/25729559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4SC00593G
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