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MicroRNA 21 Is a Homeostatic Regulator of Macrophage Polarization and Prevents Prostaglandin E(2)-Mediated M2 Generation

Macrophages dictate both initiation and resolution of inflammation. During acute inflammation classically activated macrophages (M1) predominate, and during the resolution phase alternative macrophages (M2) are dominant. The molecular mechanisms involved in macrophage polarization are understudied....

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wang, Zhuo, Brandt, Stephanie, Medeiros, Alexandra, Wang, Soujuan, Wu, Hao, Dent, Alexander, Serezani, C. Henrique
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338261/
https://ncbi.nlm.nih.gov/pubmed/25706647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115855
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