Dissecting neural differentiation regulatory networks through epigenetic footprinting

Human pluripotent stem cell derived models that accurately recapitulate neural development in vitro and allow for the generation of specific neuronal subtypes are of major interest to the stem cell and biomedical community. Notch signaling, particularly through the Notch effector HES5, is a major pa...

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Pubblicato in:Nature
Autori principali: Ziller, Michael J., Edri, Reuven, Yaffe, Yakey, Donaghey, Julie, Pop, Ramona, Mallard, William, Issner, Robbyn, Gifford, Casey A., Goren, Alon, Xing, Jeff, Gu, Hongcang, Cachiarelli, Davide, Tsankov, Alexander, Epstein, Chuck, Rinn, John R., Mikkelsen, Tarjei S., Kohlbacher, Oliver, Gnirke, Andreas, Bernstein, Bradley E., Elkabetz, Yechiel, Meissner, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336237/
https://ncbi.nlm.nih.gov/pubmed/25533951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13990
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