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Systems pharmacology approaches for optimization of antiangiogenic therapies: challenges and opportunities
Targeted therapies have become an important therapeutic paradigm for multiple malignancies. The rapid development of resistance to these therapies impedes the successful management of advanced cancer. Due to the redundancy in angiogenic signaling, alternative proangiogenic factors are activated upon...
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| 出版年: | Front Pharmacol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335258/ https://ncbi.nlm.nih.gov/pubmed/25750626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00033 |
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