Fluorescence-guided Surgery with a Fluorophore-conjugated Antibody to Carcinoembryonic Antigen (CEA), that Highlights the Tumor, Improves Surgical Resection and Increases Survival in Orthotopic Mouse Models of Human Pancreatic Cancer

BACKGROUND: We have developed a method of distinguishing normal tissue from pancreatic cancer in vivo using fluorophore-conjugated antibody to carcinoembryonic antigen (CEA). The objective of this study was to evaluate whether fluorescence-guided surgery (FGS) with a fluorophore-conjugated antibody...

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Veröffentlicht in:Ann Surg Oncol
Hauptverfasser: Metildi, Cristina A., Kaushal, Sharmeela, Pu, Minya, Messer, Karen A., Luiken, George A., Moossa, Abdool R., Hoffman, Robert M., Bouvet, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334378/
https://ncbi.nlm.nih.gov/pubmed/24499827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-014-3495-y
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