Natural Compounds as Potential Treatments of NF2-Deficient Schwannoma and Meningioma: Cucurbitacin D and Goyazensolide

HYPOTHESIS: Cucurbitacin D and goyazensolide, two plant-derived natural compounds, possess potent growth-inhibitory activity in schwannoma and meningioma cells. BACKGROUND: Currently, no FDA-approved drugs are available for neurofibromatosis type 2 (NF2)-associated schwannomas and meningiomas. Selec...

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Bibliographic Details
Published in:Otol Neurotol
Main Authors: Spear, Samuel A., Burns, Sarah S., Oblinger, Janet L., Ren, Yulin, Pan, Li, Kinghorn, A. Douglas, Welling, D. Bradley, Chang, Long-Sheng
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334125/
https://ncbi.nlm.nih.gov/pubmed/23928514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0b013e3182956169
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