Targeting CD226/DNAX accessory molecule-1 (DNAM-1) in collagen-induced arthritis mouse models

BACKGROUND: Genetic studies have pointed out that CD226 variants, encoding DNAM-1, could be associated with susceptibility to rheumatoid arthritis. Therefore, we aimed to determine the influence of DNAM-1 on the development of arthritis using the collagen-induced arthritis (CIA) mouse model. METHODS...

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Détails bibliographiques
Publié dans:J Inflamm (Lond)
Auteurs principaux: Elhai, Muriel, Chiocchia, Gilles, Marchiol, Carmen, Lager, Franck, Renault, Gilles, Colonna, Marco, Bernhardt, Guenter, Allanore, Yannick, Avouac, Jérôme
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327789/
https://ncbi.nlm.nih.gov/pubmed/25685070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0056-5
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