Specific in vitro interferon-gamma and IL-2 production as biomarkers during treatment of chronic Q fever

Background: Antibiotic treatment of chronic Q fever is cumbersome and of long duration. To monitor treatment, there is a need for alternative biomarkers. Coxiella burnetii-specific interferon (IFN)-γ and interleukin (IL)-2 production reflect the type of effector and memory T-cell response. In chroni...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Schoffelen, Teske, Wegdam-Blans, Marjolijn C., Ammerdorffer, Anne, Pronk, Marjolijn J. H., Soethoudt, Yvonne E. P., Netea, Mihai G., van der Meer, Jos W. M., Bleeker-Rovers, Chantal P., van Deuren, Marcel
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325914/
https://ncbi.nlm.nih.gov/pubmed/25729380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00093
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