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The volumes and transcript counts of single cells reveal concentration homeostasis and capture biological noise
Transcriptional stochasticity can be measured by counting the number of mRNA molecules per cell. Cell-to-cell variability is best captured in terms of concentration rather than molecule counts, because reaction rates depend on concentrations. We combined single-molecule mRNA counting with single-cel...
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| Pubblicato in: | Mol Biol Cell |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4325848/ https://ncbi.nlm.nih.gov/pubmed/25518937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1296 |
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