Thiazolidinedione treatment inhibits bile duct proliferation and fibrosis in a rat model of chronic cholestasis

AIM: To investigate the effects of troglitazone (TGZ), an anti-diabetic drug which activates peroxisome proliferator-activated receptor-γ (PPAR-γ), for liver tissue repair, and the development of ductular reaction, following common bile duct ligation (BDL) in rats. METHODS: Rats were supplemented wi...

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Veröffentlicht in:World J Gastroenterol
Hauptverfasser: Marra, Fabio, DeFranco, Raffaella, Robino, Gaia, Novo, Erica, Efsen, Eva, Pastacaldi, Sabrina, Zamara, Elena, Vercelli, Alessandro, Lottini, Benedetta, Spirli, Carlo, Strazzabosco, Mario, Pinzani, Massimo, Parola, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Inc 2005
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321905/
https://ncbi.nlm.nih.gov/pubmed/16124041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i32.4931
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