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Evaluation of prenylated peptides for use in cellular imaging and biochemical analysis.

Protein prenylation involves the addition of a farnesyl (C15) or geranylgeranyl (C20) isoprenoid moiety onto the C-terminus of approximately 2% of all mammalian proteins. This hydrophobic modification serves to direct membrane association of the protein. Due to the finding that the oncogenic protein...

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Bibliografski detalji
Izdano u:Methods Mol Biol
Glavni autori: Ochocki, Joshua D., Igbavboa, Urule, Wood, W. Gibson, Wattenberg, Elizabeth V., Distefano, Mark D.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318554/
https://ncbi.nlm.nih.gov/pubmed/24146406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-673-3_14
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