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Evaluation of prenylated peptides for use in cellular imaging and biochemical analysis.
Protein prenylation involves the addition of a farnesyl (C15) or geranylgeranyl (C20) isoprenoid moiety onto the C-terminus of approximately 2% of all mammalian proteins. This hydrophobic modification serves to direct membrane association of the protein. Due to the finding that the oncogenic protein...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4318554/ https://ncbi.nlm.nih.gov/pubmed/24146406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-673-3_14 |
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