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Targeting DNA damage response in cancer therapy
Cancer chemotherapy and radiotherapy are designed to kill cancer cells mostly by inducing DNA damage. DNA damage is normally recognized and repaired by the intrinsic DNA damage response machinery. If the damaged lesions are successfully repaired, the cells will survive. In order to specifically and...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317796/ https://ncbi.nlm.nih.gov/pubmed/24484288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12366 |
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