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Short- and Long-Term Treatment of Mouse Cortical Primary Astrocytes with β-Amyloid Differentially Regulates the mRNA Expression of L-Type Calcium Channels

BACKGROUND: It is well established that reactive astrocytes express L-type calcium channels (LTCC), but their functional role is completely unknown. We have recently shown that reactive astrocytes highly express the Ca(V)1.2 α(1)-subunit around β-amyloid (Aβ) plaques in an Alzheimer mouse model. The...

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Détails bibliographiques
Publié dans:Pharmacology
Auteurs principaux: Daschil, Nina, Geisler, Stefanie, Obermair, Gerald J., Humpel, Christian
Format: Artigo
Langue:Inglês
Publié: 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311058/
https://ncbi.nlm.nih.gov/pubmed/24435206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000357383
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