Activation of β-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells

This study investigates involvement of β-catenin signalling in regulation of p-glycoprotein (p-gp) expression in endothelial cells derived from brain vasculature. Pharmacological interventions that enhance or that block β-catenin signalling were applied to primary rat brain endothelial cells and to...

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Pubblicato in:J Neurochem
Autori principali: Lim, Joseph C., Kania, Katarzyna D., Wijesuriya, Hasini, Chawla, Sangeeta, Sethi, Jaswinder K., Pulaski, Lukasz, Romero, Ignacio A., Couraud, Pierre O., Weksler, Babette B., Hladky, Stephen B., Barrand, Margery A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303914/
https://ncbi.nlm.nih.gov/pubmed/18624906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05537.x
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