Signaling pathway STAT1 is strongly activated by IFN-β in the pathogenesis of osteoporosis

BACKGROUND: Despite extensive research, the underlying pathological mechanisms of osteoporosis are not completely understood. Recent studies have indicated a distinct role for the IFN-β/STAT1 pathway in bone metabolism. An inhibitory effect of IFN-β on osteoclastogenesis has been detected and STAT1/...

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Bibliographic Details
Published in:Eur J Med Res
Main Authors: Seeliger, Claudine, Schyschka, Lilianna, Kronbach, Zienab, Wottge, Angela, van Griensven, Martijn, Wildemann, Britt, Vester, Helen
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300729/
https://ncbi.nlm.nih.gov/pubmed/25563300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-014-0074-4
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