Cardiac myocyte–secreted cAMP exerts paracrine action via adenosine receptor activation

Acute stimulation of cardiac β-adrenoceptors is crucial to increasing cardiac function under stress; however, sustained β-adrenergic stimulation has been implicated in pathological myocardial remodeling and heart failure. Here, we have demonstrated that export of cAMP from cardiac myocytes is an int...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Sassi, Yassine, Ahles, Andrea, Truong, Dong-Jiunn Jeffery, Baqi, Younis, Lee, Sang-Yong, Husse, Britta, Hulot, Jean-Sébastien, Foinquinos, Ariana, Thum, Thomas, Müller, Christa E., Dendorfer, Andreas, Laggerbauer, Bernhard, Engelhardt, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297204/
https://ncbi.nlm.nih.gov/pubmed/25401477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74349
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