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Genomic analysis offers insights into the evolution of the bovine TRA/TRD locus

BACKGROUND: The TRA/TRD locus contains the genes for V(D)J somatic rearrangement of TRA and TRD chains expressed by αβ and γδ T cells respectively. Previous studies have demonstrated that the bovine TRA/TRD locus contains an exceptionally large number of TRAV/TRDV genes. In this study we combine gen...

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Pubblicato in:BMC Genomics
Autori principali: Connelley, Timothy K, Degnan, Kathryn, Longhi, Cassandra W, Morrison, W Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289303/
https://ncbi.nlm.nih.gov/pubmed/25408163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-994
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