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Differential Reliance on Autophagy for Protection from HSV Encephalitis between Newborns and Adults

Newborns are more susceptible to severe disease from infection than adults, with maturation of immune responses implicated as a major factor. The type I interferon response delays mortality and limits viral replication in adult mice in a model of herpes simplex virus (HSV) encephalitis. We found tha...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Wilcox, Douglas R., Wadhwani, Nitin R., Longnecker, Richard, Muller, William J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287605/
https://ncbi.nlm.nih.gov/pubmed/25569138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004580
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